Reliability Of The Lactate Scout Point-Of-Care Instrument For The Determination Of Blood L-Lactate Concentration In Sheep

 American Society for Veterinary Clinical Pathology

Please find below the abstract of the article written by Kaynar et al. under the title “Reliability Of The Lactate Scout Point-Of-Care Instrument For The Determination Of Blood L-Lactate Concentration In Sheep”. This article was published in American Society for Veterinary Clinical Pathology (Vet Clin Pathol 0/0 (2015) 1–5 ©2015)

Background: Data on accuracy and precision of the Lactate Scout point-of-care

(POC) analyzer in ovine medicine are lacking.

Objective: The purpose of the study was to assess the reliability of the Lactate Scout in sheep.

Materials and Methods: Fifty-seven sheep at varying ages with various diseases were  included. Blood lactate concentration in samples collected from the jugular vein was measured immediately on the Lactate Scout. Plasma L-lactate concentration was measured by the Cobas autoanalyzer as the reference method. Data were subjected to Student’s t-test, Passing–

Bablok regression, and Bland–Altman plot analyses for comparison and assessment of accuracy, precision, and reliability.

Results: Plasma L-lactate concentration was consistently lower than blood L-lactate concentration (3.06 _ 0.24 vs 3.3 _ 0.3 mmol/L, P < .0001). There was a positive correlation between plasma and blood L-lactate concentrations (r = .98, P < .0001). The Lactate Scout had 99% accuracy and 98% precision with the reference method. Blood (Y) and plasma (X) L-lactate

concentrations were fitted to Y = 0.28 + 1.00 _ X, with a residual standard deviation of 0.31 and a negligible deviation from the identity line (P = .93). The bias was fitted to Y = 0.10 + 0.05 _ X, with Sy.x of 0.44 (P < .07).

Conclusions: The Lactate Scout has high accuracy and precision, with a negligible bias. It is a reliable POC analyzer to assess L-lactate concentration in ovine medicine.

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