For a long time, lactate has been considered as a waste product of glycolysis which mainly caused fatigue. Many studies have been carried out and nowadays, the data suggests that lactate is not responsible for fatigue and that it is an energy source that plays a much more important role in exercise-mediated adaptations than it was previously believed.

This study aims to highlight the different lactate theories and discuss the possible role of lactate as a signalling molecule.

The authors conclude that lactate has many benefits during exercise, as lactate transport serves as an indirect regulator of muscle acidosis and is an effective energy source.

This review was performed by Minas Nalbandia and Masaki Takeda and published in 2016 by the journal Biology (Biology 2016, 5, 38; doi:10.3390/biology5040038)

Please click here to download the full article:
Lactate as a Signalling Molecule That Regulates Exercise-Induced Adaptations