Reliability and Accuracy of Six Hand-Held Blood Lactate Analysers

Journal of Sports Science and Medicine

Please find below the abstract of the article written by Jacinta M. Bonaventura, Ken Sharpe, Emma Knight, Kate L. Fuller, Rebecca K. Tanner  and Christopher J. Gore under the title “Reliability and Accuracy of Six Hand-Held Blood Lactate Analysers”, which was published in Journal of Sports Science and Medicine (2015) 14, 203 – 214

The reliability and accuracy of five portable blood lactate (BLa) analysers (Lactate Pro, Lactate Pro2, Lactate Scout+, Xpress™, and Edge) and one handheld point-of-care analyser (i-STAT) were compared to a criterion (Radiometer ABL90). Two devices of each brand of analyser were assessed using 22 x 6 mL blood samples taken from five subjects at rest and during exercise who generated lactate ranging ~1-23 mM. Each sample was measured simultaneously ~6 times on each device. Reliability was assessed as the within-sample standard deviation (wsSD) of the six replicates; accuracy as the bias compared with the ABL90; and overall error (the root mean squared error (√MSE)) was calculated as the square root of (wsSD2 and bias2). The √MSE indicated that both the Edge and Xpress had low total error (~0-2 mM) for lactate concentrations <15 mM, whereas the Edge and Lactate Pro2 were the better of the portable analysers for concentrations >15 mM. In all cases, bias (negative) was the major contribution to the √MSE. In conclusion, in a clinical setting where BLa is generally <15 mM the Edge and Xpress devices are relevant, but for athlete testing where peak BLa is important for training prescription the Edge and Lactate Pro2 are preferred.

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Reliability and Accuracy of Six Hand-Held Blood Lactate Analysers